Process for the benzoylation of organic amido compounds.



' ran srn'rns PATENT ornicn.

FREDERICK REVERDIN, OF GENEVA, SWITZERLAND, ASSIGNOR T O NEWPORTCHEMICAL WORKS, INC, 01 MILWAUKEE, WISCONSIN.

.LROCESS THE IBENZOYLATION OF ORGANIC AMIZDO COMPOUNDS.

1,296,602. No Drawing.-

To all whom it may concern:

Be it known that I, FREDERICK REVERDIN, a

citizen of the'Confederation of Switzerland, and resident of Geneva, inthe'Canton of scription thereof.

" This invention is a. process for the benzoyL' of organic compoundscontaining'one or more-amido groups.

. The benzoylation of organic compounds containing one or more amidogroups, 2'. e. NH is-generall-y made by benzoylchlorid in the presenceof a-solvent and at more or less high temperatures, It is also sometimesdone by means of benzoic anhydrid.

I" have found that the benzoylation by means of benzoyl chlorid canbesiniplified and facilitated'by the addition of a small amount ofsulfuric acid to the mixture to bebenzoylated with benzol chlorid. Thusfor instance, by dissolving trinitro-2-3-5-.p-'

anisidin in benzoyl chlorid and adding a few drops of concentratedsulfuric acid, then heating for a moment on the water bath, thebenzoy1-tr'initro-2-3-5-p ahisidin, a product that up to the presenttime has not been obtained by ordinary means, is imme Copies of thispatent may be obtained for diately obtained. 1

The same holds true for dinitro-2-4-anilin, the. known benz oylatedderivative of which had, up to the present time, been obtained only inthe presence of solvents or at high 1 temperatures.

.. The value of the new process lies in the Specification of LettersPatent.

flveeents each, by addressing Washington, D. 0."

fact that it can be used for the preparation of benzoylated derivativesthatare used industrially, as for instance for the preparation of thebenzoylated derivatives of the aminoanthraquinones, among which thebenzoyl-l-aminoanthraquinone forms an iHl-fI' portant vat dyestufi',known underthe name of algol-yellow WG; this dyestufl may be heating onthe water bath, until hy for instance, on 5 grams of amino-anthra--Patented Mar. 4, 1919.

Application filed July 16, 1918. Serial No. 245,261.

obtained, according to'my process, 'bysimdply I rochloric acid gas nolonger escapes, the mixi a quinone. According to my method the use of asolvent 'is avoided and it is no longer necessary to heat to a hightemperature (200-205 C.) at which the operation must be carriedout'according to the known process for the preparation of the saiddyestufl'.

I claim: The process herein described for the ben zoylation of. organiccompounds of the the commissioner of Iatents,

